The separation of the right side and the left side of the heart is useful to keep oxygenated and deoxygenated blood from mixing. Such separation allows a highly efficient supply of oxygen to the body. This is useful in animals that have high energy needs, such as birds and mammals, which constantly use energy to maintain their body temperature. In animals that do not use energy for this purpose, the body temperature depends on the temperature in the environment. Such animals, like amphibians or many reptiles have three-chambered hearts, and tolerate some mixing of the oxygenated and de-oxygenated blood streams. Fishes, on the other hand, have only two chambers to their hearts, and the blood is pumped to the gills, is oxygenated there, and passes directly to the rest of the body. Thus, blood goes only once through the heart in the fish during one cycle of passage through the body. On the other hand, it goes through the heart twice during each cycle in other vertebrates. This is known as double circulation
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