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Biotechnology 
(Code No. 045) 

DELETED PORTIONS CLASS XII

 
 
Under Unit V: Protein and Gene Manipulation 
 
o    Chapter 1: Recombinant DNA Technology 
Hybridization techniques, DNA library, Site-directed Mutagenesis 
 
o    Chapter 2: Protein Structure and Engineering 
3-D shape of proteins, Purification of proteins 
 
o    Chapter 3: Genomics, Proteomics and Bioinformatics:  
Introduction, Genome Sequencing projects, History of bioinformatics, Sequences and nomenclature. 
 
 

Under Unit VI: Cell Culture and Genetic Manipulation 
 
•    Chapter 1: Microbial Cell Culture and its Applications:  
Scale-up of microbial process, Biosafety issues in microbial technology 
 
•    Chapter 2: Plant Cell Culture and Applications 
Gene transfer Methods in plants 
 
•    Chapter 3: Animal Cell Culture and Applications 
Characterization of cell lines, Methods of gene delivery into cells, Scale-up of animal culture process, Tissue engineering 
 

Practicals 
 
1.    Isolation of genomic DNA (CTAB method) 
2.    Bacterial transformation using any plasmid 
3.    Restriction digestion of plasmid DNA &its analysis by gel electrophoresis 

Note

Curriculum Deduction Details (Deleted Portion only for the purpose of Annual Examination-2021)This has to be read along with the revised syllabus and also with the Alternative Calendar of NCERT.

Syllabus for Class